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Product title: L-Arginine Alpha Ketoglutarate
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L-Arginine Alpha Ketoglutarate

Product Description 

Product Name: L-Arginine Alpha Ketoglutarate

CAS No.: 5256-76-8

Molecular Formula: C17H38N8O11

Appearance: White crystalline powder

Type: Vitamins, Amino Acids and Coenzymes

Grade Standard: Pharmaceuticals Grade, Food Grade, Medicine Grade

Purity: 99%, 98%

PH: 5.5-7.0

Specific rotation: °13.5-15.5

Loss on drying: ≤0.5%

Residue on ignition: ≤0.1%

Heavy metals: ≤0.0010%

Certificates: ISO9001

Shelf life: 2 Years Proper Storage

Storage: Keep in a dry and cool place

Usage: Promote the horizontal resolution of nitric oxide in a short time, and significantly enhance energy, promote and expand muscle movement, promote the rapid growth and restore strength.

AAKG (L-arginine alpha ketoglutarate) is the combination salt of L-arginine and alpha ketoglutarate with the ratio of 2:1, thus this supplement provides both ingredients to offer synergic effects. L-Arginine is the precursor of nitric oxide (NO) to benefit cardiovascular system, immune system, male functions, and lean muscle building. 

(1)What's Alpha ketoglutarate

Alpha ketoglutarate (AKG) is a key intermediate in amino acid metabolism, and energy generating biochemistry, that is called Krebs cycle or citric acid cycle AAKG, also commonly known as Arginine AKG or Arginine Alpha Ketoglutarate, contains the essential amino acid, L-arginine. Human biochemistry depends on arginine to perform various important functions.

It assists with the elimination of ammonia by regulating the urea cycle. Arginine also serves to promote healthy functioning of the immune system. Further, it is known to be a key player in protein synthesis.

Alpha ketoglutarate is vitally important for the efficient metabolism of certain amino acids, as well as for accommodating the production of energy. AAKG is also used during heart surgeries for its vasodilator properties, helping to ensure that there are no blood delivery issues during the procedures.

It is also administered to many post-surgery patients to prevent muscular breakdown. Finally, it is effective at treating certain bacterial infections, and recurring yeast infections.

(2)Therapeutic Benefits of AAKG

Arginine AKG is therapeutically used to treat liver issues, kidney disease, cataracts and various stomach and intestinal disorders. 

Further, it is effective at relieving symptoms of erectile dysfunction and sterility in men. AAKG is also used to increase sexual desire and performance.

However, the most common usage of AAKG supplements is for bodybuilding and athletic performance purposes. Because it assists the liver in breaking down harmful substances, like ammonia, it allows for longer, less painful workouts.

L-arginine, being an amino acid, is also beneficial for the development of lean muscle mass. AAKG is favored by weightlifters, bodybuilders and various other performance athletes because it increases nitric oxide production, which in turn increased generalized vasodilation.

(3)Clinical Support for AAKG Benefits

L-arginine alpha ketoglutarate supplementation has been researched extensively in various laboratory settings. It is known that when arginine is released into the bloodstream, there is a significant increase in nitric oxide production.

With more nitric oxide present, extended muscle pumps, enhanced work capacity, elevated libido and improved recovery times are likely.

(4)The origination and development of L-Arginine Alpha Ketoglutarate

Hot selling Sport nutritions L-Arginine Alpha Ketoglutarate/AAKG in stock, Amino Acids Arginine alpha-ketoglutarate (AAKG) is a salt of the amino acid arginine and alpha-ketoglutaric acid. It is marketed as a bodybuilding supplement. The components are intermediates in the metabolism of nitric oxides, but no reputable scientific evidence shows any benefits from taking AAKG as a dietary supplement.

As of 2008, "there was no research published in peer-reviewed journals to support the assertion that an increase in nitric oxide levels promotes greater muscle protein synthesis or improves muscle strength. There is also no evidence that the arginine alpha-ketoglutarate in nitric oxide supplements have any effect on nitric oxide levels in muscles."

A recent study examined the effects of AAKG supplementation on heart rate, blood pressure, blood flow, NOx/NO2 levels, and L-arginine levels. Minimal observed changes were attributed to resistance exercise used in the experimental design, not to AAKG supplementation, although arginine levels were found to have been elevated.

Another recent study found acute AAKG supplementation made no difference in endurance or blood pressure during the course of exercise. In fact, participants that took AAKG prior to exercise had compromised endurance and strength. "Because AAKG supplementation may hinder muscular endurance, the use of these supplements before resistance training should be questioned." 

A study has found improvements in 1RM bench press and Wingate test from AAKG-use.

Production Function

1.AAKG can promote the horizontal resolution of nitric oxide in a short time, and significantly enhance energy.

2.AAKG can promote and expand muscle movement.

3. AAKG can promote the rapid growth and restore strength.


1.nutritional supplement; flavoring agent. For adult non-essential amino acids, but the body produce slower, as the essential amino acids for infants and young children, certain detoxification. Heated reaction with sugar available special flavor. Infusion of amino acids and amino acids essential component of preparation. GB2760-2001 provides for the use of food with spices. 

2.Arginine ornithine cycle is an integral component, has an extremely important physiological functions. Eat arginine, can increase the activity of liver arginase, helps the blood ammonia into urea and excreted out. Therefore, arginine for hyperammonemia, liver dysfunction and other diseases quite effective. 

3.Arginine is an amino acid base pairs, for adults, although not essential amino acids, but in some cases, such as immature or organism under conditions of severe stress, the absence of arginine, the body can not maintain positive nitrogen balance and normal physiological function. Lack of arginine may lead to the patient if the ammonia is too high, and even coma. If infants with congenital lack of certain enzymes of the urea cycle, arginine it is necessary, or can not maintain its normal growth and development.

4.Arginine important metabolic function is to promote wound healing, it can promote the synthesis of collagen, it can repair the wound. Secretion of fluid in the wound can be observed the increase of arginase activity, which also shows that the wound in the vicinity of the arginine requirement substantially. Arginine can promote micro-circulation around the wound and promote wound healing as soon as possible. 

5. Arginine immune function, prevent the degradation of the thymus (in particular the degradation of the injury), arginine supplementation can increase the weight of the thymus, promoting the growth of lymphocytes in the thymus. Arginine supplementation can reduce the volume of animals suffering from cancer, reduce tumor metastasis rate, and improve animal survival time and survival. In the immune system, in addition to lymphocytes, the phagocytic cells of the vitality and arginine. Added arginine, may activate the enzyme system, so that it can kill tumor cells or bacteria and other target cells.


Hot selling Sport nutritions L-Arginine Alpha Ketoglutarate/AAKG in stock, Amino Acids